The Role of Urodynamic Studies in Female Patients with Non-Neurogenic Lower Urinary Tract Dysfunction: A Retrospective Analysis

Abstract

Objective: To evaluate the diagnostic role of urodynamic studies (UDS) in female lower urinary tract dysfunction (LUTD) and its correlation with clinical symptoms.

Methods: A retrospective study design was followed, and 89 female patients were included (2020-2025). SPSS was used for descriptive and multivariate analyses of the association between obstetric history and pelvic surgeries with UDS findings.

Results: Forty-three (48.3%), 18 (20.2%), and 8 (9%) had no comorbidities, hypertension (HTN), and diabetes mellitus, respectively. Sixteen (18%) had urological problems, 54 (60.7%) were grand multiparous, and 20 (22.5%) had cesarean section (C-section). The mean volumes at first sensation, first desire to void, and strong desire to void were 111.83 ± 48.43 mL, 184.36 ± 70.73 mL, and 289.24 ± 93.60 mL, respectively. Urodynamic study findings for the mean maximum cystometric capacity were 370.46 ± 102.20 mL, maximum flow rate of 41.42 ± 47.04 mL/sec, post-void residual volume of 137.25 ± 144.0 mL, voided volume of 378.86 ± 164.87 mL, Valsalva leak point pressure of 7.43 ± 44.73 cm/H2O, and detrusor pressure at capacity was 10.86 ± 18.97 cm/H2O. Most patients had normal bladder compliance; 2 (2.2%) reported reduced compliance. Urethral assessment indicated that only 4 (4.5%) had obstructive urethra, stress incontinence, and 4 (4.5%) correlated with UDS and clinical symptoms (P < .05). A non-significant association was found between storage, voiding symptoms with UDS outcomes, except for hesitancy (P = .01) and straining (P = .04). Multinomial logistic regression analysis indicated no significant correlation of obstetric history and pelvic surgeries with UDS.

Conclusion: Urodynamic studies may be helpful in providing objective functional assessment in selected or complex cases. However, in the population, UDS did not consistently confirm these cases.

Cite this article as: Shamrani HM. The role of urodynamic studies in female patients with non-neurogenic lower urinary tract dysfunction: A retrospective analysis. 2026, 52, 0035, doi: 10.5152/tud.2026.26035.